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Xenical 120mg
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Thursday, 02 Jul 2026
Medication features
Hard Capsules
Xenical is a branded, prescription-only weight loss treatment used in obese patients. It contains 120mg of Orlistat. As the brand, Xenical is known for its consistent quality and clinically proven results. Taken with meals, it can block up to 30% of dietary fat from being absorbed — helping you lose weight safely and effectively when combined with a healthy, reduced-calorie diet.
- Helps to burn more calories and lose weight faster
- Prevents regaining lost weight
- Maintains your weight stability
Overview
NOTE: After selecting this product, you will need to complete a short assessment, so we can make sure this medication is suitable for you.
Xenical 120mg capsules for weight loss
Xenical is for people who are medically overweight, typically with a BMI of 30 or higher (or 28 or higher with additional weight-related conditions such as high blood pressure or type 2 diabetes). It's not suitable for pregnant or breastfeeding individuals.
What can Xenical do?
Xenical helps you lose weight, maintain a stable weight, and avoid regaining the weight you've already lost.
It works by preventing around 30% of the fat you eat from being absorbed by your body. This reduces your overall calorie intake and supports more effective weight loss — especially when combined with a low-fat diet and regular exercise.
1. Supports Effective Weight Loss
Xenical works by blocking the absorption of dietary fat — about 30% of the fat you eat passes through your system instead of being stored. When taken alongside a reduced-fat diet and regular physical activity, Xenical helps you lose more weight than a diet alone.
2. Helps You Maintain a Healthy Weight
One of the key challenges after losing weight is keeping it off. Xenical® supports long-term weight management by encouraging better food choices and reducing the chances of weight regain. This can make it easier to stick with your healthy habits.
3. Encourages Healthier Eating Habits
Xenical can act as a natural motivator to avoid high-fat foods, as eating them may cause gastrointestinal side effects. This encourages users to eat lower-fat meals, supporting a more balanced and sustainable diet over time.
4. Supports Heart Health
By aiding in weight reduction, Xenical may help improve cholesterol levels and lower blood pressure — both key factors in maintaining a healthy heart and reducing your risk of cardiovascular disease.
How to take Xenical 120mg tablets for weight loss?
Xenical 120mg Dose
Take ONE capsule up to 3 times a day, dose to be taken immediately before, during, or up to 1 hour after each main meal.
Dietary Indication
This treatment should be taken in conjunction with a well-balanced, calorie-controlled/nutritional diet. No more than 30% of your calories should come from fat, and your diet should generally be rich in fruit and vegetables.
You need to ensure to keep good levels of hydration by drinking 8-11 cups of liquid per day (2.7L).
Good to know
- Don't skip meals.
- Opt for smaller portions and use smaller plates or bowls.
- Increase your consumption of fruits and vegetables.
- Chew your food slowly.
- Avoid fried food and high-fat foods, especially deep-fried items.
- Trim excess fat and remove the skin from the meat.
For more information, please read the Patient Information Leaflet that comes with Xenical.
Xenical 120mg Side Effects:
All medications carry the risk of side effects. For Orlistat and Xenical, the common side effects include:
- Fatty or Oily Stools: You might notice your stools become oily.
- Urgent Need for the Toilet: You may have to go to the bathroom quickly.
- Frequent Bowel Movements: You might need to go to the toilet more often.
- Oily Discharge: Sometimes, you may have oily spots on your underwear.
- Gas: You could experience more gas or flatulence.
- Stomach Discomfort: You might feel some stomach pain or discomfort.
- Headaches: You might get a headache.
Most of these side effects are not very serious, and they often happen when you start taking Xenical 120mg. They tend to go away as you continue using the medicine along with a healthy diet. These side effects can be more common if you take Xenical with a very high-fat meal.
You can find more information about these side effects in the patient information leaflet.
Warnings
Xenical should not be taken if you are:
- Pregnant or breastfeeding mom
- Have a BMI less than 28
- Under 18
Xenical Safety: Taking Other Medicines
Xenical can interact with other medicines and may reduce how well they work. Tell us about any prescription medicines, over-the-counter products, or recreational substances you use so we can prescribe Xenical safely. Your safety is our priority.
Is Xenical effective and how long does it take to work?
Xenical helps with weight loss by blocking about 25–30% of the fat you eat from being absorbed, so you take in fewer calories. It works best when combined with a low-fat diet and regular exercise.
You usually start absorbing less fat within 1–2 days, but noticeable weight loss takes a few weeks to months. Most people lose 5–10% of their body weight over 6 to 12 months if they stick with the plan.
If you don’t lose at least 5% after 3 months, your doctor may stop the treatment. Since Xenical blocks fat absorption, it can also reduce vitamins A, D, E, and K, so taking a multivitamin is recommended.
Side effects like oily stools or urgency can happen, notably with high-fat meals, but usually improve as your diet changes. Overall, Xenical is a proven, MHRA-approved option that supports weight loss when paired with diet and exercise.
Which is better, Orlistat or Xenical?
Xenical is the branded version. Orlistat is the generic version. They both do the same thing in the same way to treat the same issues. Both Xenical and Orlistat contain 120mg doses of Orlistat. And there is no real difference. The only difference is the price.
Where to buy Xenical 120mg tablets online in the UK?
You can buy Xenical online from our UK-registered online pharmacy after completing a short consultation. It’s a prescription-only medicine, so your responses will be reviewed by a qualified prescriber to ensure it’s suitable for you.
Directions
Tell us about any prescription medicines, over-the-counter products, or recreational substances you use before starting Xenical. This helps us check for interactions, as Xenical can affect how other medicines work. Your safety is our priority.
Dosage
Take ONE capsule up to 3 times a day.
FAQ
How do I get Orlistat or Xenical?
After you fill out an online questionnaire, your suitability will be assessed by one of our prescribers. Once approved, your chosen weight-loss medication will be available for delivery.
What to eat when taking Xenical?
When taking Xenical, it's advised to follow a low-calorie diet. An 'orlistat diet' can help optimisze your Xenical treatment. To maximise its effectiveness, try to distribute your daily fat intake evenly across all three meals of the day.
What is the difference between Xenical and Orlistat?
Xenical is the brand name for the drug orlistat. Medically, they are identical medications, containing the same strength of 120mg orlistat.
What is the difference between Orlistat / Xenical and Alli?
Alli is the over-the-counter version of Xenical, but it's half the strength of the prescribed version. Alli contains 60mg of orlistat, while Xenical and generic prescription Orlistat contain 120mg.
Can you buy Xenical online or over the counter?
Yes, you can buy Xenical online from our UK-registered online store, Ashcroft Pharmacy. You will need to fill in an online assessment to check if it is suitable for you. If approved, our pharmacy team will prepare and send your medication to the address you've provided.
How much weight can I lose in a week with Xenical?
With Xenical, it's typically recommended to aim for a weight loss of 1-2 pounds (0.5-1 kilogram) per week, which is consistent with phase 1. The goal is to lose 5% of your body weight within the first 12 weeks. Achieving this target may allow you to continue taking Xenical during phase 3.
What is the BMI criteria for Xenical?
Xenical is suitable for adults with an initial body mass index (BMI) of 30 or more or 28 or more with at least one weight-related co-morbidity. It is used for weight control, including weight loss, weight maintenance, and preventing weight regain. Xenical should be used alongside a low-fat, calorie-controlled diet.
Does Xenical really work?
Based on reviews on Drugs.com, Xenical has an average rating of 8.3 out of 10 from 116 reviews. About 73% of reviewers reported a positive experience with the medication, while 8% reported a negative experience.
Can I drink alcohol while taking Xenical?
Studies on drug-drug interactions suggest that Xenical has no significant effect on the pharmacokinetics or pharmacodynamics of alcohol. Additionally, alcohol does not appear to affect the pharmacodynamics of orlistat.
Can I take 2 Alli instead of 1 Xenical?
No. While it might seem logical to take two Alli capsules at a time to match Xenical's dosage, but research indicates that this isn't the case. Alli prevents the absorption of 25% of the fat from your meal, whereas Xenical removes 30%, which is only a 5% difference.
Doubling the dose by taking two Alli capsules is not significantly more effective and can be considered a waste of money. One capsule at a time is sufficient.
Does Xenical reduce appetite?
Xenical doesn't control your appetite or eating habits. To work on those aspects, use the provided resources like the phase 1 manual or self-help guides. Xenical mainly helps with fat absorption.
When is the best time to take Xenical?
The best time to take Xenical is with or just before a meal, typically one hour before eating. It's important to follow the dosing instructions provided by your healthcare provider or on the medication label for the best results. Taking it with a meal helps Xenical block the absorption of dietary fat during digestion.
Delivery
Once your order has been approved by our UK medical team it will be dispatched via Royal mail. All orders are sent using a tracked and signed for service.
Royal Mail 48 (2-5 days) | £2.49
Estimated delivery within 2-3 working days. Excludes bank holidays. Not a guaranteed service.
Free standard delivery on orders over £45.
Royal Mail 24 (1-2 days) | £2.95
Estimated delivery within 1 working day. Excludes bank holidays. Not a guaranteed service.
Royal Mail Special Delivery Guaranteed by 1pm | £6.99
Order by the 2:00 PM weekday cut-off time for guaranteed delivery by 1:00 PM the next business day.
Orders placed after the cut-off on Friday will be delivered on Tuesday.
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Authored by:
Mr Suhail Jamil
Superintendent Pharmacist
GPhC Number: 2069518
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