• Melatonin

Images are for illustration purposes only.


Fastest delivery:
Wednesday, 17 Jul 2024
  • Medication features

    For Jet Lag

    Melatonin oral tablets can help you fall asleep quickly and easily, wake up more refreshed, and boost your overall well-being.

    • Proven treatment for jet lag
    • Reduces anxiety and stress levels
    • Improves memory, attention, and reaction time
    • Improves immune system
    • Reduces the risk of chronic diseases
    • Take 1 to 2 hours before bedtime
    • Patient Leaflet
    • Price Match Guarantee

    Registered UK Pharmacy Number 1039428

Order in the next for Wednesday delivery

Fastest delivery: Wednesday, 17 Jul 2024


NOTE: After selecting this product, you will need to complete a short assessment, so we can make sure this medication is suitable for you.

Buy melatonin tablets online in UK

How to Buy melatonin online for UK delivery:

You can order melatonin tablets online from UK licensed Ashcroft Pharmacy. Just fill out a quick online medical questionnaire form. Our pharmacist will check your order, and if melatonin is right for you, you'll get your medication as soon as the next working day (if this option is selected).

About melatonin

Melatonin tablets are small pills that help you sleep better. containing the synthetic hormone melatonin, which is naturally produced in our bodies.

It is a prescription-only mediaction used to prevent and reduce jet lag symptoms or treat insomnia resulting from jet lag, such as headaches and difficulty sleeping.

Actually melatonin is a hormone produced naturally by the pineal gland in the brain. It helps to regulate your sleep-wake cycle. Normally, melatonin levels increase at night to make you feel tired and to prepare your body for sleep.

Take melatonin tablets at your destination's night time to combat jet lag and adapt to the new time zone.

In several countries, melatonin is categorized as a dietary supplement, and you can buy it from their general health food stores. But in the UK, melatonin is only available with a prescription.

You may want to buy melatonin supplements from abroad, such as melatonin 'gummies', but it's not recommended as they are not authorized for sale in the UK and therefore unregulated.

Understanding Jet Lag

Jet lag is a short-term sleeping problem but unpleasant, and sometimes debilitating that occurs when your body's internal clock is out of sync with the time zone you're in, normally after long flights across different time zones.

It can cause symptoms like headache, sleep disturbances, daytime weakness, insomnia, difficulty concentrating, irritability, and digestive problems and bloating.

About Our Internal Clock: The Circadian Rhythm

Our body's internal clock (24 hour rhythm), medically known as the circadian rhythm , controls brain functions like sleep-wake cycles, hormone release, and body temperature. When we rapidly cross time zones, our circadian rhythm or body clock struggles to adjust to the new light-dark cycle, leading to jet lag.

It usually takes a few days, but for some, it can last up to a week or more for your body to adapt to the new time zone. It's commonly said that it takes about one day for each hour of time zone difference for your body clock to adjust to a new time zone, but this can vary.

If you're traveling to a different time zone for just a few days, some people find it easier to stick to their body clock, keeping their sleep and meal times based on their home time zone.

To minimize its effects, adjusting your sleep schedule before travel, staying hydrated, getting exposure to natural sunlight, and using medications like melatonin to regulate sleep can be helpful strategies.

How melatonin works for jet lag treatment?

Melatonin oral tablets help to reset the body's sleep-wake cycle to the new time zone. This can help to reduce the symptoms of jet lag and improve sleep quality.

Melatonin primarily regulates day and night cycles. Darkness triggers increased melatonin production, signaling the body to prepare for sleep.

Light reduces melatonin, signaling wakefulness. Low melatonin levels can lead to difficulty falling asleep. Taking melatonin supplements can aid in improving sleep and helping individuals fall asleep.

Benefits of using melatonin oral tablets?

The benefits of using melatonin oral tablets include:

  • Improved overall well-being
  • Reduced jet lag symptoms
  • Improved sleep quality
  • Improved sleep onset

Is melatonin safe?

Melatonin oral tablets are generally safe and well-tolerated for most people. However, they can cause side effects in some people, such as headache, dizziness, nausea, and daytime drowsiness.

It is essential to talk to your doctor before taking melatonin oral tablets, especially if you have any underlying health conditions or are taking any other medications.

Can anyone take melatonin?

Most people can take it for short periods. However, some people should not take melatonin, including

  • Pregnant or Breastfeeding Women
  • People with autoimmune disorders, such as multiple sclerosis or rheumatoid arthritis
  • People with seizure disorders
  • People taking certain medications, such as blood thinners or antidepressants

How to use melatonin for jet lag?

It is important to start taking melatonin on the first day of your travel and continue taking it for 2-3 days after you arrive at your destination.

To use melatonin oral tablets, take a supplement 30-60 minutes before bedtime in the destination time zone. For example, if traveling from New York to London, you would take melatonin 30-60 minutes before bedtime in London time.

  • Choose a high-quality melatonin supplement.
  • Start with the lowest dose available.
  • Do not cut the pill.
  • Take a time-released melatonin pill one to three hours before bed.
  • If you cannot fall asleep within three to four hours, take another time-released melatonin pill.
  • For awakenings at night that last less than one hour, take a sublingual melatonin pill.
  • For awakenings at night that last more than one hour, take a time-released melatonin pill and a sublingual melatonin pill.

Here are some additional tips for using melatonin:

  • Take melatonin at the same time each night. It helps to regulate your body's natural sleep-wake rhythm.
  • Avoid taking melatonin too close to bedtime. Melatonin can make you drowsy, so it is important to give it time to work before you go to bed.
  • Create a relaxing bedtime routine like taking a warm bath, reading a book, or listening to soothing music.
  • Avoid caffeine and alcohol before bed. These substances can interfere with sleep.
  • Ensure your bedroom is dark, quiet, and kept at a comfortable temperature.


Melatonin can interact with specific medications, including blood thinners and antidepressants. Talk to your doctor before taking melatonin, especially if you have any underlying health conditions or are taking any other medications.


Melatonin oral tablets are a safe and effective way to improve sleep quality and reduce the symptoms of jet lag. If you are struggling with sleep problems, talk to your doctor about whether melatonin oral tablets are right for you.

Patient Information Leaflet (from EMC):

NameMr Suhail Jamil
RoleSuperintendent Pharmacist
GPhc Number2069518



Reducing Jet Lag Without Medication

  • Before you travel, adjust your bedtime closer to your destination's bedtime and ensure you're well-rested.
  • Stay calm and relaxed during your journey.
  • Stay hydrated by drinking plenty of water, especially during the flight.
  • Avoid alcohol.
  • Move around on the plane when possible.
  • Set your watch to the destination time at the beginning of the flight.
  • Sleep during the journey according to the destination's nighttime hours.
  • Upon arrival, try to sleep and eat according to the destination's times.
  • Keep your sleeping environment dark at night, even if you're awake.
  • Avoid daytime naps.
  • Spend time outdoors, particularly in the afternoon when traveling west and in the morning when traveling east. Natural light helps with adjustment, or you can use a SAD (Seasonal Affective Disorder) light at these times.


Recommended dose

The recommended dose of melatonin for jet lag treatment is 0.5-5 milligrams. Beginning with a minimal dosage and adjusting as required is the recommended approach.

Start taking Melatonin as soon as possible after your symptoms begin. Swallow the tablet whole with a glass of water, with or without food, three times a day for 5 days.


  • What is Melatonin?

    Melatonin is a sleep hormone that is produced naturally in the body to regulate your sleep cycle.

  • How long does melatonin take to start working?

    Melatonin takes effect within 20-40 minutes (some up to 1-2 hours). So take it 30-60 minutes before bedtime.

  • Where can I buy Melatonin online in the UK?

    You can order Melatonin from UK-registered Ashcroft Pharmacy at the lowest price only £14.99, by completing a short online assessment. This helps ensure the medication is suitable for you.

  • How long will I take melatonin to treat insomnia?

    You'll usually take melatonin for 1-4 weeks to treat insomnia, up to 13 weeks in some cases. If it doesn't work after 13 weeks, try lifestyle changes or see a doctor again. For some types of insomnia, it can be a long-term treatment.

  • How to take melatonin for jet lag?

    Dosage: The usual dose is 1 tablets (3mg) 30-60 mins. before bedtime. Your doctor may recommend 2 tablets (6mg) based on your needs.

    Timing: Take melatonin when you arrive at your destination at your normal bedtime. However, avoid taking it before 8pm or after 4am.

    Duration: You can use melatonin for up to 5 nights in a row.

  • How does melatonin work for jet lag?

    Melatonin helps reset your body's clock to the new time zone, easing jet lag symptoms like fatigue and insomnia. Take 1-2 tablets at bedtime, between 8pm and 4am, for up to 5 nights. Talk to your doctor first.

  • Will you sleepwalk with Melatonin?

    Taking Melatonin is not linked to sleepwalking.

    If you have a history of sleepwalking or are concerned about the possibility, it's best to consult your doctor before taking melatonin.

    Resources that you may find helpful:

    National Sleep Foundation:
    Mayo Clinic:
    American Academy of Sleep Medicine:

  • Can I get addicted to melatonin?

    No, you won't get addicted to melatonin if taken as directed for short-term sleep issues. However, if you've been using it for a long time, consult your doctor before stopping. They can help you safely stop taking melatonin.


  • Can I buy melatonin supplements at a health food shop?

     Unfortunately, in the UK, you cannot buy melatonin supplements at a health food shop. Melatonin is a prescription-only medicine in the UK, and it's not available for purchase over the counter.

  • Will it affect my contraception or HRT?

    Melatonin won't affect your birth control. It is safe to take with hormonal contraceptives like the pill and emergency contraception.

    However, the combined pill and  hormone replacement therapy (HRT) can boost the amount of melatonin in your body. This is usually safe and harmless. Talk to your doctor if you have any concerns. 

  • Can I drive or ride a bike while taking Melatonin?

    Don't drive or ride a bike if melatonin makes you sleepy, dizzy, or affects your concentration. This applies to both starting and continuing treatment.

    Wait until any side effects disappear before driving or operating machinery. You may also want to consult a doctor or pharmacist if you're unsure.

    Remember, driving under the influence can be dangerous and illegal. Always prioritize safety and make responsible decisions.

    Learn More> GOV.UK has more information on the law on drugs and driving.

  • Can I drink alcohol while taking melatonin?

    Don't Drink Alcohol with Melatonin: It's Dangerous! Both make you sleepy, leading to overly deep sleep. You may struggle to wake up or breathe properly. Avoid alcohol completely while taking melatonin.

  • Is there any food or drink I need to avoid?

    Yes, you need to avoid drinks containing caffeine (including tea, coffee, cola, and energy drinks) and alcohol while taking melatonin. These substances can interfere with melatonin's effectiveness in promoting sleep.

Side Effects

Side effects of melatonin tablets include:

Melatonin oral tablets are generally safe and well-tolerated for most people. However, they can cause side effects in some people, such as headache, dizziness, nausea, anxiety, and daytime drowsiness.

o see all possible side effects of Melatonin tablets, please read the patient leaflet carefully.



Once your order has been approved by our UK medical team it will be dispatched via Royal mail. All orders are sent using a tracked and signed for service.

Royal Mail 48 (2-5 days) | £3.49

Estimated delivery within 2-3 working days. Excludes bank holidays. Not a guaranteed service.

Free delivery on orders over £50.

Royal Mail 24 (Next working day) | £4.99

Estimated delivery within 1 working day. Excludes bank holidays. Not a guaranteed service.

Royal Mail Special Delivery Guaranteed by 1pm | £9.95

Order by the 2:00 PM weekday cut-off time for guaranteed delivery by 1:00 PM the next business day.

Orders placed after the cut-off on Friday will be delivered on Tuesday.

Price Comparison

Medication Ashcroft Pharmacy
2mg x20 tablets x 2mg £19.99
Order now
2mg x30 tablets x 2mg £25.99
Order now
2mg x10 tablets x 2mg £14.99
Order now
Similar Items


Medication Ashcroft Pharmacy
2mg x20 tablets x 2mg £19.99
Order now
2mg x30 tablets x 2mg £25.99
Order now
2mg x10 tablets x 2mg £14.99
Order now