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Mebeverine 135mg Tablets
In Stock
Tuesday, 16 Jun 2026
Medication features
IBS Treatment
Mebeverine, also known as mebeverine hydrochloride, is a gut muscle relaxant that works directly on intestinal smooth muscles, easing cramps from conditions like Irritable Bowel Syndrome (IBS). You should feel better 1 to 3 hours after taking it.
- Anti-spasmodic medicine
- Relief from pain & discomfort
- Works within 30 minutes
Overview
NOTE: After selecting this product, you will need to complete a short assessment, so we can make sure this medication is suitable for you.
Buy Mebeverine online for IBS
Mebeverine is a popular medicine used to relieve symptoms of irritable bowel syndrome (IBS) and similar digestive conditions. It works by relaxing the muscles in the gut, helping to reduce spasms and ease discomfort.
It can help manage symptoms such as:
- Stomach pain and cramps
- Bloating
- Diarrhoea or constipation
Mebeverine is commonly sold under brand names such as Colofac IBS and Aurobeverine, all of which contain mebeverine hydrochloride as the active ingredient.
It’s typically available in:
- Tablets (e.g. 135mg)
- Modified-release capsules (200mg)
- Combination sachets with ispaghula husk (a fibre supplement)
What is Mebeverine used for?
Mebeverine is primarily used to treat IBS. It may also be recommended for other functional bowel conditions that cause intestinal spasms.
Typical symptoms it helps relieve include:
- Abdominal cramping
- Bloating and excess wind
- Urgency or irregular bowel movements
If you have ongoing digestive symptoms, it’s important to speak to a GP or pharmacist before starting treatment.
Mebeverine vs Buscopan: what’s the difference?
Both mebeverine and Buscopan are used to relieve IBS symptoms, but they’re used slightly differently:
Mebeverine is typically taken regularly to help prevent symptoms
Buscopan is usually taken as needed for sudden crampsBuscopan may act more quickly for short-term relief, while mebeverine is better suited to ongoing symptom control. Your choice will depend on how frequently your symptoms occur.
Who may not be able to take Mebeverine tablets?
Mebeverine hydrochloride tablets are not suitable for everyone. Consult a doctor, pharmacist, physician, or chemist before using it to ensure that it is safe for you.
Do not take Mebeverine if:
- You are allergic to Mebeverine or any ingredient in the medicine
- You have a galactose intolerance
- You have paralytic ileus, a condition causing constipation due to an inactive gut
- You are pregnant or breastfeeding
Who may not be able to take mebeverine tablets?
Some people should not take Mebeverine hydrochloride tablets. Consult a physician or chemist before using it to ensure that it is safe for you.
- People allergic to Mebeverine or any ingredient in the medicine
- Individuals with galactose intolerance, a rare inherited condition
- Those with paralytic ileus, a condition causing constipation due to inactive gut
- Pregnant or breastfeeding women.
Directions
Dosage
Dosage – how to take Mebeverine for IBS
Always take Mebeverine exactly as your doctor or pharmacist instructs you.
Standard tablets (135 mg): Take one tablet three times a day, ideally about 20 minutes before meals.
Slow‑release capsules (200 mg): Take one capsule twice a day, with your meals spaced evenly through the day.
Take each tablet or capsule whole with a drink of water; do not chew or crush it.
Try to space your doses evenly throughout the day, following your prescriber’s instructions.
If your symptoms improve, your doctor or pharmacist may advise you to stop taking mebeverine. Many people take it only when symptoms are causing discomfort.
If you forget a dose: Skip the missed dose and take the next one at the usual time. Do not take two doses at once.
Duration of treatment: You’ll usually take mebeverine only while your IBS symptoms flare up. Stop when you feel better unless your clinician has advised otherwise.
Warnings
Medicines and other treatments: Mebeverine can generally be taken with most regular prescriptions and painkillers such as paracetamol and ibuprofen. (nhs.uk) Avoid taking more than one IBS‑specific remedy at the same time unless your doctor says it’s okay, this is because similar drugs often work in the same way and are unlikely to add benefit but may increase unwanted effects.
Pregnancy and breastfeeding:
If you are pregnant, think you might be pregnant, planning a pregnancy, or breastfeeding, talk to your doctor or pharmacist before taking mebeverine.
Your clinician may advise you to stop taking Mebeverine if you are pregnant or breastfeeding.
You can drink alcohol while taking mebeverine, but be aware that alcohol itself may make IBS symptoms worse.
FAQ
What is IBS (Irritable Bowel Syndrome)?
IBS is a common condition that affects the gut, causing abdominal pain, cramping, bloating, and changes in bowel habits. Pain occurs when the muscles of the intestine contract too strongly or irregularly. Mebeverine helps relieve these spasms and associated symptoms.
What are the common symptoms of IBS?
Symptoms vary, but often include:
- Stomach pain or cramping
- Diarrhoea, constipation, or alternating episodes of both
- Bloating and excess gas
- Hard, lumpy, or narrow stools
Is Mebeverine available over the counter?
Mebeverine is available on prescription. In some cases, certain forms may be purchased from pharmacies.
How long should I take Mebeverine for IBS?
Take Mebeverine during IBS flare-ups and stop when your symptoms improve, usually within 1–2 weeks. If symptoms persist or worsen, speak with your doctor.
What if I forget a dose of Mebeverine?
Skip the missed dose and continue with your normal schedule. Do not take a double dose. Using reminders, alarms, or asking your pharmacist for tips can help you remember.
What if I take too much Mebeverine?
An accidental extra dose is unlikely to cause serious harm. Contact your pharmacist or doctor if you’re concerned.
When can I expect relief from symptoms?
Mebeverine usually starts working within an hour, with relief often noticeable within 1–3 hours.
Does Mebeverine have a laxative effect?
No. Mebeverine does not act as a laxative. However, combination products like Fybogel Mebeverine include ispaghula husk to help with constipation linked to IBS.
Can Mebeverine cause weight changes?
No. Mebeverine relaxes gut muscles and does not affect metabolism or calorie intake.
Will Mebeverine affect my contraception?
Mebeverine does not interfere with any form of contraception, including the combined pill and emergency contraception.
Are there foods or drinks I should avoid while taking Mebeverine?
You can eat and drink normally, but it’s helpful to avoid foods that trigger your IBS, such as caffeine, fizzy drinks, or fried food.
Are there other medicines for IBS?
Yes. Other antispasmodics include peppermint oil, Colofac and Buscopan (hyoscine butylbromide). Both help relax gut muscles and relieve cramps, but they work differently from Mebeverine.
Is Buscopan the same as Mebeverine?
No. Buscopan and Mebeverine are different antispasmodics, each working in its own way to ease intestinal muscle spasms.
When should I take Mebeverine in relation to food?
Take Mebeverine about 20–30 minutes before meals. This ensures the medicine is absorbed before digestion starts, making it more effective. Taking it after food may slow absorption.
Can Mebeverine cause constipation?
While uncommon, Mebeverine may occasionally cause constipation because it relaxes the gut muscles. If constipation persists, speak with your doctor.
Will Mebeverine make me go to the toilet more often?
Mebeverine itself does not usually increase bowel frequency. Its main effect is to relax the gut muscles and relieve cramps. If you notice changes that concern you, consult your healthcare provider.
Side Effects
Side effects of Mebeverine
This medication has potential side effects just like any other medicine, although not everyone will experience them. If you experience any of the following symptoms, you should stop taking the medication and visit your doctor right away:
- Severe allergic reactions resulting in breathing difficulties,
- Swelling of the face, neck, lips, tongue, or throat
Additional side effects include the potential for allergic reactions, which can manifest as rashes, swelling, hives, redness, or inflammation of the skin. Speak with your physician if you experience any side effects.
Information
Mebeverine tablets Patient Information Leaflet
Mebeverine tablets specification
| Medicine type | An antispasmodic |
| Active ingredient | Mebeverine |
| Dosage | ONE tablet THREE times a day |
| How it works | by relaxing the muscles in your gut, which can help to relieve cramps and spasms. |
| Starts working | within 1 hour after taking it, and you should feel better within 1 to 3 hours after taking it. |
| About side effects | Mebeverine is generally well-tolerated |
| How long to take | up to 2 weeks |
| PregnancyWarning | Not recommended during pregnancy. |
| FoodWarning | Take minimum 20 minutes before meals |
| Brand | Generic |
| BreastfeedingWarning | Not recommended |
| AlcoholWarning | This product is not affected by alcohol |
| Strength | 135mg |
| Pack size | 100 tablets |
Delivery
Once your order has been approved by our UK medical team it will be dispatched via Royal mail. All orders are sent using a tracked and signed for service.
Royal Mail 48 (2-5 days) | £2.49
Estimated delivery within 2-3 working days. Excludes bank holidays. Not a guaranteed service.
Free standard delivery on orders over £45.
Royal Mail 24 (1-2 days) | £2.95
Estimated delivery within 1 working day. Excludes bank holidays. Not a guaranteed service.
Royal Mail Special Delivery Guaranteed by 1pm | £6.99
Order by the 2:00 PM weekday cut-off time for guaranteed delivery by 1:00 PM the next business day.
Orders placed after the cut-off on Friday will be delivered on Tuesday.
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Written and reviewed by our qualified team
Authored by:
Mr Suhail Jamil
Superintendent Pharmacist
GPhC Number: 2069518
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