omeprazole tablets for acid reflux

What you need to know about Omeprazole

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Omeprazole is a prescription treatments that treat a variety of diseases. This blog will cover all about Omeprazole medicine.


What is Omeprazole?

Omeprazole is a prescription medicine that comes either in tablet, capsule, or liquid. Omeprazole treatment is used to treat acid reflux, heartburn, and ingestion.

How does Omeprazole work?

Omeprazole | Acid Reflux Treatment is a proton pump inhibitor (PPI). Proton pumps, also known as hydrogen-potassium pumps, are found along the stomach's inner lining. The acid-release pumps are in charge of releasing acid into the stomach.

PPIs, such as omeprazole, prevent acid from being released into the stomach, lowering acidity.

Omeprazole takes around an hour to stop stomach acid production, and its effects peak roughly 2 hours after you take the pill. Omeprazole's effects can last up to three days.

Keyfacts about Omeprazole?

  • Do not take omeprazole longer than 2 weeks without consulting with your doctor. Always consult with your pharmacist if you bought your omeprazole from a pharmacy.
  • Omeprazole has common side effects such as headaches, stomach pains, and diarrhea. The side effects go away on their own after taking the medicine.
  • Omeprazole is taken once a day.
  • Omeprazole starts working 3 days after you take it. You will see the full effectiveness of the medicine within 4 weeks.
  • Avoid taking alcohol while taking Omeprazole medicine. Alcohol irritates the stomach lining therefore worsening your symptoms.
  • Drug Interactions - Omeprazole can interact with some medications, affecting how they work in your body. Always disclose all medications and supplements you're taking to your doctor before starting omeprazole treatment.
  • The Importance of Diagnosis - Don't embark on a self-diagnosis and treatment journey with omeprazole. Underlying conditions like ulcers or ZES require proper diagnosis and a personalized treatment plan devised by your doctor.
  • Short-Term vs. Long-Term Use - Omeprazole is generally considered safe for short-term relief of acute conditions like heartburn or ulcers. However, long-term use (over a year) might require closer monitoring by your doctor due to potential side effects like vitamin B12 deficiency or an increased risk of bone fractures, particularly in older adults.
  • Alternative Approaches - For mild heartburn, exploring lifestyle modifications and natural remedies like ginger or licorice root (always consult your doctor before trying any supplements) might offer some relief. Discussing these alternatives with your doctor can help you determine the best course of action for your specific situation. Remember, omeprazole is a powerful tool, but it's not always the only solution.

Side effects of Omeprazole

Always check the side effects of omeprazole from the patients' leaflets. You may encounter different types of side effects when taking Omeprazole. These side effects include Common side effects, serious effects, and long-term side effects.

Common side effects.
Common side effects affect 1 in 100 people. The common side effects include:

  • Stomach pain 
  • Headaches 
  • Diarrhea 
  • Constipation 
  • Nausea 

Serious side effects 

If you experience serious side effects you need to consult your doctor for further treatment. Serious side effects 1 in1000 people include:

  • Severe diarrhoea 
  • Darker pee
  • Joint pains.Getting a red rash on body parts such as cheeks and arms when exposed to the sun.
    Developing a yellow skin.
  • Feeling tired

Long-term side effects 
Magnesium levels in your blood lower after taking Omeprazole for more than 3 months. If you realize that Omeprazole is not working for you, ensure that you consult your doctor for a change in medication.Long-term effects of Omeprazole include:

  • Fluctuating of the bones 
  • Infection in the guts 
  • Vitamin B12 deficiency 

Omeprazole dosage.

Omeprazole is available in different forms: Liquid and tablet. Tablets are available in 10mg,20mg, and 40mg while liquid tablets are available in 2mg and 4mg.

Your pharmacist may recommend a lower dosage for your child or if you have liver problems. Below is how you should take your Omeprazole dosage.

  • For heartburn and acid reflux you should take 20mg to 40mg a day 
  • For stomach ulcers, you should take 20 to 40 mg a day 
  • For indigestion, you should take 10 to 20mg a day 

Uses of Omeprazole

There are other applications of Omeprazole. They include

Zollinger-Ellison Syndrome (ZES) -  ZES, a rare condition that leads to excessive acid production. Here, omeprazole steps in as a long-term control mechanism. By, suppressing acid production at its source, it prevents complications like ulcers and esophageal damage.
H. Pylori Eradication - This stealthy bacteria, H. pylori, can penetrate the stomach lining, causing irritation and contributing to ulcers. Omeprazole joins forces with antibiotics to form a powerful duo. Omeprazole reduces the stomach's acidic environment, making it easier for antibiotics to target and eliminate H. pylori, preventing future ulcer recurrence.
Esophagitis - This inflammation, known as esophagitis, can cause discomfort and even damage the esophageal lining. Omeprazole's acid-reducing ability comes to the rescue. Creating a less acidic environment promotes healing and reduces inflammation in the esophagus, alleviating symptoms and preventing further damage.
Nonsteroidal Anti-Inflammatory Drug (NSAID)-Induced Ulcers - NSAIDs, while effective for pain relief, can irritate the stomach lining, increasing the risk of ulcers. Omeprazole can be used as a preventive measure in individuals at high risk of developing NSAID-induced ulcers. It helps shield the stomach lining from the damaging effects of these medications.

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How to take Omeprazole

A liquid Omeprazole is prescribed for children and people who cannot swallow Omeprazole tablets. The pharmacist makes the liquid Omeprazole for you and issues a spoon or a syringe to you so that you can take the right amount of the medicine.

Omeprazole capsules and tablets should be swallowed whole with a drink of water. If you have a problem swallowing your tablets you can break them into granules and add them to water or soft foods such as yogurt.

Depending on the severity of your symptoms, your doctor may recommend you take the medicine once or twice a day.

If your doctor recommends you take the medicine once in a day, take your medication in the morning with or without food.

If your doctor recommends you to take Omeprazole twice a day, take 1 dose in the morning and the other dose in the evening.


✅ Avoid taking 2 doses at once if you have forgotten to take your dose as usual.

✅ Share your medical history with your doctor before taking the Omeprazole prescription.

✅ Only use Omeprazole when needed during pregnancy

✅ If you experience serious side effects, consult your doctor immediately 

✅ Before having surgery always describe to your doctor the type of prescriptions you are taking.

✅ In case of overdose get help from a nearby doctor 

Storage and disposal

You should keep omeprazole in an airtight container away from children's sight and reach. Keep Omeprazole away from light, excess heat, and moisture.

Dispose of your unused Omeprazole medicines through a take-back program. Avoid disposing of the medicine together with your house litter to prevent consumption by pets, children, and other people.


Understanding omeprazole goes beyond its uses. Here are some frequently asked questions to shed light on common concerns:

Is omeprazole safe for everyone?
While generally safe for short-term use, omeprazole might not be suitable for everyone. Consult your doctor before using it, especially if you have underlying health conditions, are pregnant, or breastfeeding.

Can I take omeprazole over the counter (OTC)?
Yes, omeprazole is available in both prescription and OTC forms. However, OTC omeprazole is typically for short-term relief of mild heartburn. For any ongoing stomach issues, consult your doctor to determine the best course of action.

How long does it take for omeprazole to work?
It can take a few days for omeprazole to reach its full effectiveness. Be patient and continue taking it as prescribed by your doctor.

What are the potential side effects of omeprazole?
Common side effects include headache, diarrhea, constipation, stomach pain, and nausea. In rare cases, long-term use might be linked to vitamin B12 deficiency or an increased risk of bone fractures. Discuss these potential side effects with your doctor.

Are there any natural alternatives to omeprazole?
For mild heartburn, lifestyle modifications like dietary changes, weight management, and stress management can offer relief. Additionally, some natural remedies like ginger or licorice root (always consult your doctor before trying supplements) might be helpful. Discuss these options with your doctor to see if they might be suitable for you.

Can I stop taking it?
Never abruptly stop taking omeprazole without consulting your doctor. They can help you develop a safe tapering-off plan if appropriate for your situation.

Can lifestyle changes help stomach acid?

Lifestyle changes can help stomach acid. The lifestyle changes include: Maintaining a healthy weight, avoiding spicy foods, avoiding caffeinated drinks, and eating your dinner 3 hours before bed.

Can I take Omeprazole with antacids?

Yes, you can take Omeprazole with antacids.

Will Omeprazole affect my contraception?

Omeprazole doesn't affect regular contraception. However, Omeprazole may affect the effectiveness of Ulipristal contraception.

Can I drive or ride the bike after taking Omeprazole?

It's not safe for you to drive or ride a bike if you experience blurred vision and dizziness after taking Omeprazole.

Are there lifestyle remedies for preventing gut problems?

There are lifestyle habits that can prevent gut problems.They include:

Dietary Discipline - Identify and avoid trigger foods that worsen your symptoms. Spicy, acidic, and fatty meals can all contribute to heartburn and other stomach issues.
Weight Management - Excess weight puts pressure on your abdomen, including your stomach, which can worsen acid reflux. Maintaining a healthy weight through a balanced diet and regular exercise can significantly improve gut health.
Stress Management - Chronic stress can wreak havoc on your digestive system. Techniques like yoga, meditation, or deep breathing can help manage stress and potentially reduce stomach discomfort.
Sleep Hygiene - Elevating the head of your bed by 6-8 inches while sleeping can help prevent stomach acid from splashing upwards, reducing the risk of heartburn. Additionally, avoiding heavy meals close to bedtime can also be beneficial.

Bottom line

Omeprazole is a valuable tool in the fight against various stomach ailments. By understanding its unique applications, potential considerations and you can make informed decisions about using this medication for optimal gut health. 

Visit Ashcroft Pharmacy to communicate with our qualified pharmacist and receive the right treatment for acid reflux.

Reviewed By 

Name Mr Suhail Jamil 
Role Superintendent Pharmacy 
GPhc Number 2069518

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