Understanding the Side Effects of Omeprazole: What You Need to Know

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Some Side effects of omeprazole may include:

  • Back, leg, or stomach discomfort
  • Bleeding or crusting sores on the lip’s blisters
  • Red or murky urine
  • Chronic mouth ulcers or sores
  • Urination that is difficult, scorching
  • Painful fever
  • Frequent need to urinate
  • General sensation of discomfort or sickness
  • Itching, skin rash
  • Joint pain
  • Lack of appetite
  • Pains and cramps in the muscles
  • Eyes that are red or inflamed
  • Skin redness, soreness, itching, burning, or peeling 

Feeling sick (nausea), experiencing a stomach-ache, or having wind (flatulence); belly (abdominal) discomfort, being sick (vomiting).

Avoid rich or spicy foods and stick to basic meals. Inform your doctor if your symptoms are severe or do not go away.

For diarrhoea, consume lots of water. Inform your doctor if it persists or worsens. Constipation: eat a well-balanced diet and drink plenty of water every day. Headache, drink plenty of water and ask your pharmacist for a pain reliever that is appropriate for you. Inform your doctor if the headaches persist.

You have joint discomfort as well as a red skin rash, particularly on sun-exposed areas of your body such as your arms, cheeks, and nose—these are symptoms of a rare disorder known as subacute cutaneous lupus erythematosus. Even if you've been taking omeprazole for a long time, this can happen.

Acid Reflux Treatment

Severe side effects:

Serious side effects are rare, affecting fewer than one in every 1,000 people. Consult your doctor about the following side effects: 

These are uncommon issues, but you should visit your doctor immediately if you have them:

Breathing difficulties, wheezing, skin rashes or itching, tightness in the chest, or swelling of the face, lips, or throat are all symptoms of an allergic response.   skin rash, skin blistering or peeling, or any other changes in your skin, especially in areas of skin exposed to sunlight or if you're experiencing joint discomfort. Jaundice is the yellowing of your skin or the whites of your eyes, as well. A severe allergic reaction: In rare situations, omeprazole can cause a severe allergic response (anaphylaxis).  If you wish to learn more about the potential adverse effects of omeprazole, talk to your doctor or pharmacist, or read the medication leaflet. You should notify your doctor if you believe you have had an adverse effect.

Long-term omeprazole side effects

Proton pump inhibitors, such as omeprazole, may modestly raise your chances of fracturing a bone in your hip, wrist, or spine, especially if used at high dosages for more than a year. If you are over the age of 65, have osteoporosis, or have risk factors for osteoporosis, it is critical that you receive adequate calcium and vitamin D to avoid bone issues. If you don't obtain enough calcium and vitamin D from your diet, your doctor may advise you to take a supplement. Consult your doctor for further information. 

Omeprazole may infrequently lower the amount of magnesium in your blood, especially if you use it for more than three months or if you simultaneously take digoxin or a diuretic. Fatigue, muscular spasms or twitching, convulsions, disorientation, dizziness, and an elevated heart rate are some of the symptoms. Inform your doctor if you have any of these symptoms, as you may require a blood test to determine the level of magnesium in your blood. 

If you are taking omeprazole for a long time, such as for Zollinger-Ellison syndrome, the low acid levels in your intestines may impair the absorption of vitamin B12 (cyanocobalamin). If your doctor believes you are at high risk for this, he or she may recommend vitamin B12

Symptoms of overdose

  • Blurred vision
  • Blurred vision
  • Disorientation
  • Dry mouth
  • Flushing, headache
  • Increased perspiration