Naproxen Dosage Guide: How Much to Take Safely

What is Naproxen and how it works

Naproxen works by reversibly inhibiting cyclooxygenase (COX) enzymes. There are two main types of COX enzymes, COX-1 and COX-2.

• COX-1 produces prostaglandins that maintain gastric mucosal integrity and platelet-initiated blood clotting.
• COX-2 mediates pain and inflammation. By inhibiting COX-2 enzymes, it reduces the level of prostaglandins and therefore alleviates related symptoms such as pain and inflammation.

Naproxen is available in the form of:

• Gastro-resistant tablets
• Uncoated tablets
• Liquid suspensions

Why Does the Correct Dose Matter?

If you take more Naproxen than you need, you increase your risk of experiencing negative side effects such as gastrointestinal bleeding, ulcers and kidney problems. Taking a Naproxen dose that is too low for your condition could result in your pain and inflammation not being adequately treated. Always follow medical guidance when using Naproxen or any other medication. The course of treatment and dosage that is prescribed for you will be listed on your prescription and on the label of your pharmaceutical box. If you are unsure about the right dose or have concerns, speak with a doctor or pharmacist.

Excipients

can vary between different formulations, such as tablets and suspensions, as well as between different brands and manufacturers. If you have any allergies or intolerances, read the patient information leaflet before using your medication and contact your pharmacist for further information.

Naproxen Dosage Per Day

Most Common Adult Dose

For most adults, naproxen is usually taken at 250–500mg every 6–8 hours (as prescribed), depending on the condition being treated. A 500mg dose is usually prescribed for more severe pain or inflammation, for example, during arthritis flare-ups. In the UK, higher doses or long-term use require a prescription from your GP. For short-term pain relief, lower-dose naproxen (250mg) is available over the counter. Always read the patient leaflet carefully and never exceed the recommended dosage amount.

For most adults, naproxen is usually taken at 250–500mg every 6–8 hrs. (as prescribed), depending on the condition being treated. 

A 500mg dose is usually prescribed for more severe pain or inflammation, for example, during arthritis flare-ups.

In the UK, higher doses or long-term use require a prescription from your GP. For short-term pain relief, lower-dose naproxen (250mg) is available over the counter.

Always read the patient Leaflet carefully and never exceed the recommended dosage amount.

Recommended Dosage for Pain Relief

• Pain and inflammation in rheumatic disease: 0.5–1 g (500–1000 mg) daily in 1–2 divided doses.
• Pain and inflammation in musculoskeletal disorders, Dysmenorrhoea (period pain): Initially 500 mg for 1 dose, then 250 mg every 6–8 hours as required.
• Acute gout: Initially 750 mg for 1 dose, then 250 mg every 8 hours until attack has passed.
• Acute migraine: 500 mg for 1 dose, to be taken in combination with sumatriptan as soon as migraine symptoms develop.

Naproxen doses are available in a variety of strengths and are used to treat a variety of diseases and health issues (ranging from 250mg to 750mg strength tablets).

Naproxen 500mg and 250mg tablets are available at Ashcroft Pharmacy. We also offer gastro-resistant tablets to guarantee that the risk of stomach-related adverse effects is as low as possible.

How long should you take Naproxen?

The duration depends on your condition, Naproxen’s strength, and your response to the medication. Normally, for acute conditions, doctors prescribe Naproxen for a few days or weeks. For chronic or severe conditions, Naproxen is taken long term. Prolonged use of Naproxen can irritate your stomach; therefore, gastroprotective treatment is recommended alongside. When the long-term use of Naproxen is required, the doctor may prescribe gastroprotective medicine such as Omeprazole or Lansoprazole. Take Naproxen under medical supervision, and always consult your healthcare professional about its safety, risks, and correct use.

Naproxen is an anti-inflammatory pain reliever that is used to treat pain and inflammation caused by a variety of medical disorders (such as arthritis, gout or menstrual pain). When it comes to using Naproxen for pain relief, it's critical to get the dosage right and follow your doctor's or pharmacist's advice. It is typically recommended that you do not take Naproxen in large doses for long periods of time. Doing so makes you more likely to experience adverse and dangerous side effects, especially to your stomach and gut (such as stomach ulcers or gastrointestinal bleeding). However, if you use Naproxen as directed, it is a very safe and effective pain and inflammation medication. It is perfectly safe to take Naproxen every day (and numerous times a day) for pain relief for brief periods of time. You can Order Naproxen tablets online from Ashcroft Pharmacy in a dosage of 250mg. Simply fill out our online consultation form to order Naproxen tablets for fast-acting and efficient pain treatment. We will be able to dispatch your medication for next-day delivery once your order has been approved by our pharmacy team.

Sources

Naproxen Patient Information Leaflet: https://www.medicines.org.uk/emc/product/543/pil

https://www.nhs.uk/medicines/naproxen/