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Tadalafil Tablets for ED

From£7.49

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Fastest delivery:
Tuesday, 16 Jun 2026
  • Medication features

    Tadalafil tablets for ED (generic Cialis) are a prescription treatment that can help you get and keep an erection when you’re sexually aroused. Often called the “weekend pill”, tadalafil can stay active in your body for longer than some other ED tablets, giving you more flexibility around intimacy.

    • Works for 80-85% of men
    • Lasts for up to 36 hrs
    • Take up to 2 hrs. before sex
    • Tadalafil 2.5mg & 5mg available
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Overview

Cialis is the well known branded version of Tadalafil. A cheaper alternative is generic Tadalafil, which contains the same active ingredient

NOTE: After selecting this product, you will need to complete a short assessment, so we can make sure this medication is suitable for you.

  • Overview of Taking Tadalafil Tablets for ED

    Tadalafil (generic Cialis) is a longer-lasting erectile dysfunction treatment. Generic tadalafil contains the same active ingredient as branded Cialis, and it works in the same way.

  • Strengths of Tadalafil Treatment

    If this is your first time taking tadalafil, a 10mg dose is often recommended, but the right strength depends on your health profile and how you respond to treatment. Tadalafil is available as an on-demand tablet (commonly 10mg or 20mg) or as a lower-dose daily option (2.5mg or 5mg). On-demand tablets can remain effective for up to 36 hours.

  • What are Tadalafil tablets for ED?

    Tadalafil is the active ingredient used in Cialis, a well-known ED treatment. Tadalafil tablets are used to treat erectile dysfunction (ED) in adult men by supporting blood flow to the penis when you are sexually stimulated.


    Because tadalafil can remain active for longer, many men choose it for the flexibility it offers, rather than needing to time sex within a short window.


    For further information on Tadalafil treatment, refer to the official NHS overview of Tadalafil as a medication: About Tadalafil - NHS

  • How To Buy Tadalafil Tablets Online in the UK

    Erectile dysfunction is more common than you might think and is nothing to be ashamed of. Some drugs can help with the condition, ones you can discreetly purchase online to save you from having to purchase them over the counter.


    You can buy Tadalafil tablets online from an approved, accredited pharmacy. Ashcroft Pharmacy is an official GPhC-registered pharmacy. We can discreetly prescribe and deliver Tadalafil tablets for ED. 


    All you need to do is complete a short online consultation. This assessment helps our prescriber check that tadalafil is safe and suitable for you, including reviewing your symptoms, medical history, and any current medications.


    If approved, our pharmacy team will dispense your Tadalafil treatment and deliver it to your chosen address in discreet packaging.


    Need help before you start? Contact our team or Call 01274 050750.

  • Why Choose Tadalafil?

    Tadalafil tablets are a popular ED option because they offer a longer window of effectiveness, and generic tadalafil is typically more affordable than the branded version.


    Generic tadalafil contains the same active ingredient as Cialis, has the same intended effect, and is prescribed in the same strengths. The main difference is cost.

  • Why Tadalafil Tablets Are Nicknamed The “Weekend Pill”

    Tadalafil is also known as the weekend pill because it can remain effective for up to 36 hours. If you take a tablet on Friday night, it can still work on Sunday morning. This extended duration has made Tadalafil a popular choice for many.

    This does not mean you will have an erection for 36 hours. It means the medication stays active in your system, so you may find it easier to get an erection during that time when you are aroused.

    Choosing Tadalafil tablets for ED is a popular option for many men due to this added convenience.

  • Tadalafil effectiveness

    According to clinical studies conducted by The Electronic Medicines Compendium (EMC), in 80% of cases, Tadalafil showed a significant improvement in erectile function, allowing successful sexual intercourse up to 36 hours. And it's proven that it helps to achieve and maintain erections more effectively compared to a placebo.

    Learn More About Tadalafil Effectiveness for ED Treatment:

    Ashcroft Pharmacy Guide by Our Medical Prescribers:


    How Effective is Tadalafil for Treating Erectile Dysfunction?

    US National Library of Medicine Article:


    US National Library of Medicine: Effect of tadalafil 5mg daily treatment


    Remember, Tadalafil may not be effective on the first try. Use it at least eight times before giving up or considering other options

     
    Erectile dysfunction categoryMildModerateSevere
    Tadalafil improvement86%83%72%

    Results of taking Tadalafil tablets for ED vary depending on the underlying cause of the ED (for example, stress, circulation issues, diabetes, or medication side effects).

    If tadalafil does not work the first time, timing and context can matter. Taking your tablet with enough time before sex, avoiding excessive alcohol, and allowing for sexual stimulation can improve results. If you are not getting the desired effect, do not increase your dose yourself. Speak to a prescriber to review your options.

  • Taking Tadalafil for the First Time

    If you’re using tadalafil for the first time:

    • Take the tablet at least 30 minutes before sex.
    • Swallow with water (with or without food).
    • Allow time for arousal, as the medicine will not work without stimulation.
    • Avoid heavy alcohol intake, which can reduce performance and increase side effects.
    • Do not combine tadalafil with other ED tablets.
  • Who Should Avoid Tadalafil Treatment

    Tadalafil may not be suitable if you:

    • Take nitrate medicines for chest pain (angina), or use recreational “poppers”.
    • Have been advised not to have sex for medical reasons.
    • Have certain heart conditions, or have recently had a heart attack or stroke.
    • Have severe liver or kidney problems (dose adjustment may be required).
    • Have had serious side effects from PDE-5 inhibitors before.

    Always disclose all medicines and supplements in your consultation so interactions can be checked safely.

  • Alternative ED treatments

    Not all men require an effective medication for up to 36 hours. There are other oral PDE5 treatments like:

     

  • Tadalafil daily (2.5mg, 5mg) vs Cialis '36 hours'

    On-demand tadalafil is taken before sex and may remain effective for up to 36 hours. Daily tadalafil is a lower-dose option taken once a day, which can suit men who have sex more frequently and prefer a more spontaneous approach.

    Most men take Cialis as needed, typically 10mg or 20mg, which stays effective for up to 36 hours. However, men who need ED treatment two or more times a week should consider taking a daily low-dose tablet, either 2.5mg or 5mg, which provides continuous treatment without ups and downs.

    Your prescriber will advise whether daily or on-demand tadalafil is the safer option for you.

Directions

Tadalafil should only be taken to help get, or maintain, an erection. Tadalafil should be taken 30 minutes before engaging in sexual activity, and no more than one dose should be taken per day.

Tadalafil tablets come in multiple strengths, including 2.5mg, 5mg, 10mg, and 20mg. Your prescriber will advise which option is appropriate based on your assessment.

  • On-demand tadalafil: commonly 10mg taken before sex (dose may be adjusted if needed)
  • Daily tadalafil: 2.5mg or 5mg taken once daily for suitable patients
  • Do not take more than one dose in 24 hours unless your prescriber has advised a daily regimen.

You can read NHS guidance on Tadalafil dosage here:

NHS - How and when to take tadalafil

Taking Tadalafil With Other Medicines

Do not use Tadalafil if you are taking:

  • Viagra/sildenafil, Levitra/vardenafil, or Spedra/avanafil within 24 hours.
  • HIV medications like Indinavir and ritonavir.
  • Antifungal drugs, Itraconazole or ketoconazole.
  • Nitrates for angina.
  • Recreational drugs like amyl nitrate ('poppers').
  • Blood pressure medications are called alpha-blockers.
  • Antibiotics such as erythromycin, clarithromycin, or rifampicin.
  • Anticonvulsants like phenobarbital, phenytoin, or carbamazepine.

Always list your current medicines during the consultation so interactions can be checked properly.

Dosage

Take ONE tablet at least 30 minutes before sexual activity

  • Tadalafil tablets have four strengths: 2.5mg, 5mg, 10mg, and 20mg.
  • Most men take a 10- or 20mg tablet when required.
  • The 2.5mg and 5mg doses are for daily use.
  • Some men might find that an occasional 5mg tablet is sufficient.
As required dosage (10mg, 20mg)
  • Most men use Tadalafil as needed, about 30 minutes before they plan to have sex.
  • A single tablet of Tadalafil 10mg or 20mg remains effective for up to 36 hours.
  • Men typically take a tablet when they anticipate sexual activity within the next 36 hours.
  • The highest recommended dose is 20mg within 24 hours.
  • 10mg and 20mg is not recommended for daily use.
Daily dosage (2.5mg, 5mg):
  • If you need ED treatment often, take a small 2.5mg or 5mg tadalafil tablet daily. Only Tadalafil (including branded Cialis) offers this option.
  • The usual daily dose is 5mg, taken around the same time daily. You can reduce it to 2.5mg if it's better for you. These small daily pills provide continuous treatment, But it may take a few days to work fully.

Before you start taking it every day, talk to your regular doctor

Warnings

If this is the first time you are taking Cialis or Tadalafil, then 10mg is recommended for you. Cialis and Tadalafil come in two forms, a one-pill 26-hour form (10mg or 20mg) or a daily treatment (2.5mg or 5mg). Effects of the 10mg and 20mg tablets will last for up to 36 hours.

Additional considerations:
  • Alcohol and grapefruit juice may impact the effectiveness of Tadalafil.
  • Some men experienced reduced sperm count, but it's unlikely to affect fertility.
  • Tadalafil can cause dizziness; be cautious when operating vehicles or machinery.
  • Tadalafil tablets may contain lactose and trace amounts of sodium.
  • The maximum recommended dose for individuals with severe kidney problems is 10mg, and daily use is not recommended.
  • Tadalafil is not meant for individuals under 18 or for women. Keep all medications out of children's reach.

FAQ

  • How Does Tadalafil Work?

    Tadalafil belongs to a group of medicines called PDE-5 inhibitors. When you are sexually stimulated, tadalafil helps the blood vessels in the penis relax and widen, which supports increased blood flow. This can make it easier to achieve and maintain an erection.

    Tadalafil does not increase sexual desire, and it will not work without sexual stimulation. If low libido is a concern, it’s important to speak to a clinician.

  • Is Tadalafil Safe?

    Tadalafil is a licensed and well-studied treatment for erectile dysfunction, and it is suitable for many men. However, it is not suitable for everyone, and that’s why the consultation is essential.

    Common side effects can include headache, flushing, indigestion, nasal congestion, and muscle aches. If side effects are troublesome or persistent, seek medical advice.

    For clinically reviewed prescribing information, see NICE official guidance:

    National Institute for Health and Excellence (NICE): Drugs: Tadalafil

  • Do I have erectile dysfunction because I am old?

    Erectile dysfunction is more common in older men, particularly those aged 40 or above. This is because older men usually have pre-existing conditions such as high blood pressure, diabetes, high cholesterol and obesity, which all contribute to erectile dysfunction. The older you get, the lower your testosterone levels become as well, which also contributes to erectile dysfunction.

  • Can being tired cause erectile dysfunction?

    Yes. When you are tired, you have a decreased sex drive (libido), so it is harder to gain and maintain an erection. This also happens when you are lacking in fitness.

  • Can masturbating cause erectile dysfunction?

    If you are masturbating several times in a short period of time, then yes, you may experience difficulties in getting and maintaining an erection.

  • Can cycling cause erectile dysfunction?

    Excessive cycling has been linked to causing erectile dysfunction, especially if the seat is applying pressure to the testicles. This applies pressure to the nerves at the bottom of the penis, which contributes to erectile dysfunction. The same thing can occur if you wear excessively tight clothing for long periods of time consistently.

  • How can I treat erectile dysfunction

    This is dependent on the cause of ED, so it is very important to consult your GP to identify the cause. Once the cause is known, it is easier to suggest a treatment plan. Treatment options include medicine and lifestyle changes.

  • Is erectile dysfunction reversible?

    This depends on the cause of erectile dysfunction. If it is due to underlying medical problems, it is often quite difficult to completely reverse erectile dysfunction.
    However, there are many treatment options available to help live with the condition. Some causes are reversible, such as excessive drinking and smoking, excessive cycling and excessive masturbation.

  • Can taking vitamins help my erectile dysfunction?

    Vitamins should not be used as the main treatment for erectile dysfunction, as there is not much evidence for it.
    However, vitamin C, vitamin E and vitamin B complex are believed to assist in men suffering from ED. Vitamin C and vitamin B complex are thought to help with blood flow, and vitamin E is thought to help with producing testosterone, which may lead to improvement of ED.

  • Which drug is best for erectile dysfunction?

    All erectile dysfunction drugs work in the same way, but they have slightly different properties. Different drugs work differently for everyone, so individuals will have different preferences. First-line treatment in most cases is sildenafil, which is also the active ingredient in Viagra. Another popular drug is Tadalafil for erectile dysfunction, which is the active ingredient in Cialis.

  • Can I take Viagra if I have diabetes or cardiovascular disease?

    Yes. It should not be a problem to take Viagra or any other ED treatment if you have diabetes or cardiovascular problems.
    You must check that none of your current medications will interact with the ED treatment that you would like to buy. Our online consultation will guide you through checking if any of your current medications interact with the ED treatment. You must be sure to answer all questions honestly.

  • Will just taking my ED tablet give me an erection?

    No. Sexual stimulation is required for these tablets to work. You will not get an erection just from taking the tablet.

  • What are the benefits of treating erectile dysfunction?

    Treating ED will not only improve your life in the bedroom, but it may also improve your life overall. It may improve your self-esteem, boost your confidence, increase your blood flow and circulation, and it may even inspire you to live a healthier lifestyle.

  • Can I prevent myself from getting erectile dysfunction?

    You may not be able to prevent it completely, as one reason males may experience ED is due to ageing, which is not preventable.
    However, there are many things you can do to lower your risk of getting ED. This includes: drinking less alcohol, quitting smoking, remaining sexually active to promote body positivity, keeping your fitness levels high, and eating a balanced and healthy diet.

  • What should I do if my erectile dysfunction symptoms persist?

    Do not suffer in silence. It is important to discuss the matter with your partner and your doctor for emotional and professional support. It is nothing to be ashamed about, and it is a common condition. Speaking to a doctor may help identify the underlying cause, which will then make it easier to treat the symptoms.

  • What dose of ED medication should I take?

    It is advised that you start off at the lowest dose available and see how well that works. Take a stronger dose the next time if the starting dose was insufficient.

  • Can I split my tablet to save money?

    This is not recommended by the manufacturer, but it is commonly done. Bear in mind that splitting a pill will also halve your dose.

  • Do ED tablets always work?

    ED Pills do work for most men. However, if the penile nerves are damaged or blood circulation is restricted, the tablets may not always work. Men with low testosterone levels may also be resistant to tablet treatment. If one tablet does not work, it is worth trying a different drug. If your symptoms persist, you should consult your GP.

  • Does having ED mean that there is something wrong with my health?

    In many cases of ED, the underlying cause is nothing to worry about. However, it is extremely important to identify the cause of your ED by speaking to your doctor in order to rule out serious health issues.

Side Effects

The most common side effect is temporary changes in vision color (bluish or yellowish), which are harmless and go away once the medication wears off. Similar visual changes can occur with other ED treatments.

Other common side effects (1%-10% of users) include

  • Facial flushing
  • Arm or leg pain
  • Back pain
  • Headaches
  • Dizziness
  • Muscle aches
  • Stuffy nose
  • Indigestion
  • Nausea

A rare but severe side effect is priapism, a painful, prolonged erection lasting hours. Priapism requires immediate hospital treatment to prevent penile damage.

  • Serious side effects are rare. To minimize side effects, use the lowest effective tablet strength.
  • Check the patient leaflet in the medication packaging for a complete list of side effects.

Delivery

Once your order has been approved by our UK medical team it will be dispatched via Royal mail. All orders are sent using a tracked and signed for service.


Royal Mail 48 (2-5 days) | £2.49

Estimated delivery within 2-3 working days. Excludes bank holidays. Not a guaranteed service.

Free standard delivery on orders over £45.

Royal Mail 24 (1-2 days) | £2.95

Estimated delivery within 1 working day. Excludes bank holidays. Not a guaranteed service.

Royal Mail Special Delivery Guaranteed by 1pm | £6.99

Order by the 2:00 PM weekday cut-off time for guaranteed delivery by 1:00 PM the next business day.

Orders placed after the cut-off on Friday will be delivered on Tuesday.

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Written and reviewed by our qualified team

Authored by:

Mr Suhail Jamil

|

Superintendent Pharmacist

GPhC Number: 2069518

Order Monday to Friday before 14:00pm to guarantee next day delivery