- Available in 250mg tablets
- Used to prevent malarial infection when travelling
- Weekly tablet form
NOTE: After selecting this product, you will need to complete a short assessment, so we can make sure this medication is suitable for you.
Lariam is an antimalarial medication used to prevent malaria infection from the parasite P. falciparum when travelling to high risk areas. The active ingredient of Lariam is 250mg of Mefloquine hydrochloride. Lariam works by targeting the malarial parasite and destroying it, therefore the parasite is unable to infect you.
Patient Information Leaflet (from EMC): https://www.medicines.org.uk/emc/files/pil.9670.pdf
The usual dose is one 250mg tablet a week on the same day each week. The tablet should be swallowed whole with water after a meal.
How long do I have to take Lariam for?
Lariam should be started 2 to 3 weeks before you depart, continued during your trip and taken for 4 weeks after your return.
How is Lariam different from Malarone?
Both are used to prevent malaria, however they each contain different active ingredients and have different directions for administration. Lariam also has more side effects, which are more severe as well.
How effective is Lariam?
No treatment is 100% effective but Lariam will greatly reduce the chance of malaria infection. Prevention of bites is the most effective prevention of malaria. This can be done by using insect repellent that contains DEET, using an insecticide containing malaria net and wearing long clothing to cover the skin in the evenings and nights.
Can I take Lariam if I am pregnant?
No. Do NOT take Lariam if you are pregnant or breastfeeding. You should wait at least 3 months after the last dose of Lariam if you are considering becoming pregnant.
Side effects include:
- Severe anxiety or depression
- Stomach pain
- Nausea or vomiting
- Sleeping problems
- Psychotic and paranoid behaviour, such as suicidal thoughts, hallucinations, self-endangering behaviour, changes in mood/behaviour and seizures.
If you experience any of these whilst taking Lariam, stop taking treatment immediately and contact your doctor, who can provide an alternative antimalarial medication.